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Side 207Side Studies / Research

Subject

Population Genetics

Purpose

Genetic variation in populations studied through allele frequencies, drift, selection, mutation, migration and demographic history.

Structure

05 movesFormal systemV0

Definitions → structures → relations → proof → application

01 · Model

Connect evolutionary mechanisms to changing allele frequencies.

Population genetics supplies a formal language for how inheritance and population processes shape variation over generations.

01

Allele frequencies

Represent genetic variation at population scale without confusing population frequencies with individual genotypes.

02

Genetic drift

Model random sampling effects that can change frequencies even without differences in fitness.

03

Selection

Relate genotype-dependent reproductive success to expected frequency change while keeping environment and dominance explicit.

04

Migration & structure

Study gene flow and subdivision as forces that connect or differentiate populations.

05

Demographic inference

Use patterns of variation to reconstruct population size change, bottlenecks, admixture and ancestry under explicit models.

02 · Distinctions

Keep the boundaries visible.

Do not conflate

genetic drift ≠ measurement noise

Do not conflate

ancestry ≠ race

Do not conflate

selection ≠ adaptation proof

03 · Questions

Questions that organize the Side.

01

When can the same genetic pattern be generated by selection versus demography?

02

How does population structure create misleading associations?

03

Which historical events are identifiable from present-day genetic variation and which are not?

04 · Evidence

What should carry weight here?

Use model checking, simulation and independent historical or archaeological evidence where possible; demographic assumptions strongly condition inference.